July 21, 2006 Weekend Box Office
| 1 |
  |
Pirates of the Caribbean: Dead Man's Chest |
$35,215,201 |
$321,899,233 |
| 2 |
N/A |
Monster House |
$22,217,226 |
$22,217,226 |
| 3 |
 |
Lady in the Water |
$18,044,396 |
$18,044,396 |
| 4 |
N/A |
You, Me and Dupree |
$12,767,590 |
$45,299,080 |
| 5 |
 |
Little Man |
$11,025,108 |
$40,636,230 |
| 6 |
N/A |
Clerks II |
$10,061,132 |
$10,061,132 |
| 7 |
N/A |
My Super Ex-Girlfriend |
$8,603,460 |
$8,603,460 |
| 8 |
 |
Superman Returns |
$7,375,213 |
$178,342,711 |
| 9 |
N/A |
The Devil Wears Prada |
$7,361,991 |
$97,508,460 |
| 10 |
 |
Cars |
$4,947,198 |
$229,485,636 |
|
